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[The data show that mildronate treatment significantly improved animal performance in water maze and social recognition tests, lowered amyloid-? deposition in the hippocampus, increased expression of the microglia marker Iba-1, and decreased AChE staining, although it did not alter expression of proteins involved in synaptic plasticity (GAP-43, synaptophysin, and GAD67).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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